[Candida albicans endocarditis after pulmonary artery banding]

M Talvard1, S Paranon, Y Dulac

  • 1Service de cardiologie pédiatrique, hôpital des Enfants, 330, avenue de Grande-Bretagne, BP 3119, 31000 Toulouse cedex, France.

Insights

This case report details a rare instance of Candida albicans endocarditis in an infant following pulmonary artery banding. Prompt surgical intervention and antifungal treatment led to a satisfactory outcome.

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases

Background:

  • Endocarditis is rare in infants, with Candida albicans infections being exceptionally uncommon.
  • Pulmonary artery banding is a palliative procedure for congenital heart defects, sometimes used in unstable infants.

Observation:

  • A 7-month-old infant, post-pulmonary artery banding for a ventricular septal defect, developed systemic Candida infection.
  • Cardiac failure manifested later without typical inflammatory signs, revealing complications of the banding and pseudoaneurysm.

Findings:

  • Candidal endocarditis was diagnosed, complicated by a pulmonary artery perforation due to an infected pseudoaneurysm and banding migration.
  • Histopathology confirmed multisensitive Candida albicans in vegetations.

Implications:

  • This case highlights the potential risks of Candida endocarditis associated with pulmonary artery banding in infants.
  • Early detection and combined surgical and antifungal management are crucial for favorable outcomes in such rare pediatric cases.

Related Concept Videos

Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...