Related Experiment Video
Updated: Jun 22, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Glucagonoma diagnosed by arterial stimulation and venous sampling (ASVS)
Yukiyoshi Okauchi1, Takao Nammo, Hiromi Iwahashi
1Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita. okauchi@imed2.med.osaka-u.ac.jp
Abstract:
To identify the location of pancreatic endocrine tumors, arterial stimulation and venous sampling (ASVS) is known to be useful for insulinoma and gastrinoma, but its usefulness for glucagonoma has not been verified to date. Here we report a case of glucagonoma that was diagnosed by ASVS with calcium loading, in which an approximately 6-fold increase of glucagon was observed in the splenic artery territory. MEN1 gene analysis verified the presence of a mutation and the glucagonoma was confirmed after operation. In conclusion, ASVS could be useful for the diagnosis of glucagonoma.
Related Concept Videos
Hypoglycemia and Glucagon
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by the...

