Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Familial abdominal chemodectomas with associated cutaneous angiolipomas.

S P Lee, G I Nicholson, G Hitchcock

    Pathology
    |April 1, 1977
    PubMed
    Summary

    Two brothers presented with cutaneous angiolipomas and malignant retroperitoneal chemodectomas, suggesting a potential familial syndrome. Both succumbed to metastatic chemodectomas, with a possible similar condition in two other siblings.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A FFAR1 full agonist restores islet function in models of impaired glucose-stimulated insulin secretion and diabetic non-human primates.

    Frontiers in endocrinology·2022
    Same author

    The Singaporean public beliefs about the causes of mental illness: results from a multi-ethnic population-based study.

    Epidemiology and psychiatric sciences·2017
    Same author

    Cockayne Syndrome due to a maternally-inherited whole gene deletion of ERCC8 and a paternally-inherited ERCC8 exon 4 deletion.

    Gene·2015
    Same author

    Role of protein kinase C-η in cigarette smoke extract-induced apoptosis in MRC-5-cells.

    Human & experimental toxicology·2014
    Same author

    A case of successful perinatal outcome and management of microinvasive cervical cancer diagnosed in the 3rd trimester of pregnancy.

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology·2014
    Same author

    Cord blood T cells retain early differentiation phenotype suitable for immunotherapy after TCR gene transfer to confer EBV specificity.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2012

    Area of Science:

    • Oncology
    • Genetics
    • Pathology

    Background:

    • Familial cancer syndromes represent a significant area of oncological research.
    • Understanding the genetic basis of rare tumor types is crucial for diagnosis and treatment.

    Observation:

    • The study describes two brothers with concurrent cutaneous angiolipomas and intra-abdominal retroperitoneal chemodectomas.
    • Both affected brothers experienced fatal malignant dissemination of their chemodectomas.

    Findings:

    • A potential familial syndrome involving angiolipomas and chemodectomas is proposed.
    • The occurrence in siblings suggests a possible inherited predisposition to these neoplasms.

    Implications:

    • This case highlights the importance of considering familial cancer syndromes in patients with rare tumor combinations.

    Related Experiment Videos

  • Further research into the genetic underpinnings of this syndrome may inform diagnostic strategies and therapeutic approaches for affected families.