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Related Experiment Video

Updated: Jun 22, 2026

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Published on: September 14, 2013

C. difficile infection - a tool for improving practice and reducing rates.

Ann-Marie Aziz¹, Pauline Murphy

¹University Hospital South Manchester, Wythenshawe Hospital, Machester.

British Journal of Nursing (Mark Allen Publishing)

|June 16, 2009

Summary

Hospitals can reduce healthcare-acquired infections (HAIs) like Clostridium difficile infection (CDI) by implementing Root Cause Analysis (RCA) tools. This strategy enhances teamwork and improves patient care outcomes.

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Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

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Published on: September 14, 2013

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Published on: May 25, 2017

Area of Science:

Infectious Diseases
Healthcare Management
Patient Safety

Background:

Clostridium difficile infection (CDI) is a significant healthcare-acquired infection (HAI).
Older patients are particularly susceptible to CDI following antibiotic treatment.
Increasing CDI mentions on death certificates highlight the need for effective interventions.

Purpose of the Study:

To evaluate the implementation and impact of the Root Cause Analysis (RCA) tool for CDI management.
To assess the effectiveness of RCA in reducing CDI rates and improving hospital practices.

Main Methods:

A Manchester hospital piloted the Root Cause Analysis (RCA) tool for confirmed CDI cases starting in February 2008.
The RCA tool was refined based on clinician feedback before full implementation.
The study examined the embedding of the RCA tool and the management of the change process.

Main Results:

The implemented RCA tool significantly improved clinical practices and collaborative working.
Enhanced teamwork was observed following the introduction of the RCA tool.
A reduction in CDI rates was achieved through the use of the RCA tool.

Conclusions:

The Root Cause Analysis (RCA) tool is an effective strategy for reducing healthcare-acquired infections (HAIs) such as CDI.
Successful implementation requires adapting tools based on clinician feedback and managing the change process effectively.
The adoption of RCA has led to tangible benefits in patient care and infection control.