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Extraskeletal Ewing's sarcoma
1Department of Radiology and Diagnostic Imaging (40), King Khalid University Hospital, PO Box 286522, Riyadh 11323, Kingdom of Saudi Arabia. manar970@hotmail.com
Saudi Medical Journal
|June 16, 2009
Summary
This study details two rare cases of extraskeletal Ewing's sarcoma, a cancer that can occur outside of bones. Histological analysis confirmed the diagnosis in both posterior mediastinum and kidney tumors.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Extraskeletal Ewing sarcoma (EES) is a rare malignant neoplasm.
- It typically affects children and young adults, but can occur in adults.
- EES can arise in various soft tissues, making diagnosis challenging.
Observation:
- A middle-aged man presented with a large posterior mediastinal mass initially suspected as lymphoma.
- A young male patient had a left kidney mass with vascular invasion, initially diagnosed as renal cell carcinoma.
- Both cases showed heterogeneous masses on CT imaging with distinct clinical presentations.
Findings:
- Histological examination revealed both the mediastinal and renal masses were extraskeletal Ewing's sarcoma.
- The initial radiological diagnoses differed significantly from the final histopathological findings.
- This highlights the potential for misdiagnosis based on imaging alone.
Implications:
- Rare presentations of extraskeletal Ewing's sarcoma can mimic more common malignancies.
- Accurate histological analysis is crucial for definitive diagnosis of EES.
- Increased awareness of EES in diverse locations can improve diagnostic accuracy and patient outcomes.
