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Forequarter amputation for malignancy.

J Rickelt1, H Hoekstra, F van Coevorden

  • 1Department of Surgical Oncology, Erasmus Medical Centre/Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands.

The British Journal of Surgery
|June 16, 2009
PubMed
Summary
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Forequarter amputation (FQA) offers a potential cure for shoulder girdle cancers like sarcoma. While it improves local control, FQA does not impact survival in cases of axillary metastasis.

Area of Science:

  • Surgical Oncology
  • Orthopedic Oncology
  • Cancer Surgery

Background:

  • Forequarter amputation (FQA) is a critical surgical intervention for shoulder girdle malignancies.
  • Understanding the role of FQA in surgical oncology is essential for treatment planning.

Purpose of the Study:

  • To evaluate the efficacy and outcomes of forequarter amputation (FQA) in patients with malignant disease of the shoulder girdle.
  • To determine the impact of FQA on survival rates and local recurrence in various cancer types.

Main Methods:

  • Retrospective analysis of 40 patients who underwent forequarter amputation (FQA).
  • Included diagnoses: soft-tissue sarcoma (28 patients) and recurrent breast cancer (5 patients).
  • Nine patients required concurrent chest wall resection.

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Main Results:

  • Overall survival at 1, 2, and 5 years was 71%, 59%, and 38% respectively.
  • Curative FQA in 32 patients yielded 1, 2, and 5-year survival rates of 90%, 75%, and 48%.
  • Median survival for palliative FQA was 5 months; 5-year survival for soft-tissue sarcoma was 41%.

Conclusions:

  • Forequarter amputation (FQA) can be curative for locoregional diseases like sarcoma.
  • FQA does not improve survival in patients with axillary metastasis but may enhance local control and quality of life.