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[Studies on xanthones from aerial parts of Polygala sibirica]
Yuelin Song1, Yong Jiang, Sixiang Zhou
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Objective:
To investigate the chemical constituents of the aerial parts of Polygala sibirica systematically.
Methods:
The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral data.
Result:
Ten compounds were isolated and identified as 6-hydroxy-1, 2, 3, 7-tetramethoxy xanthone (1); 1, 2, 3, 6, 7-heptamethoxy xanthone (2); 1, 7-didydroxy-2, 3-methylenedioxy xanthone (3); 1, 7-dihydroxy-2, 3-dimethoxy xanthone (4); 1, 3, 7-trihydroxy-2-methoxy xanthone (5); 1, 6, 7-trihydroxy-2, 3-dimethoxy xanthone (6); alpha-spinasterol (7); alpha-spinasterolic-3-O-beta-D-glucoside (8); squalene (9) and polygital (10).
Conclusion:
Compounds 1-10 were isolated from this species for the first time.
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