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Healthy-years equivalent: wounded but not yet dead
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Expert Review of Pharmacoeconomics & Outcomes Research
|June 17, 2009
Summary
The healthy-years equivalent (HYE) offers an alternative to the quality-adjusted life-year (QALY) for health technology assessment. Recent research suggests HYE is feasible and addresses QALY limitations, potentially reviving its use.
Area of Science:
- Health Economics
- Health Technology Assessment
- Outcome Measurement
Background:
- The quality-adjusted life-year (QALY) is the dominant health outcome measure, despite known flaws in utility elicitation and strong assumptions.
- The healthy-years equivalent (HYE) was proposed as an alternative to address QALY limitations.
- The primary criticism of HYE is its perceived difficulty and impracticality in estimation.
Purpose of the Study:
- To review empirical applications of the healthy-years equivalent (HYE).
- To identify recent methodological advances in estimating HYE.
- To assess the feasibility and potential revival of HYE as a health value measure.
Main Methods:
- Literature review of empirical HYE applications.
- Analysis of recent advances in preference-elicitation methods for HYE.
- Evaluation of HYE's feasibility and comparison to QALY.
Main Results:
- Despite historical debate, the QALY remains dominant.
- Empirical research and methodological advancements demonstrate HYE's feasibility.
- Recent advances address criticisms of HYE's preference-elicitation methods.
Conclusions:
- The healthy-years equivalent (HYE) shows promise as a viable alternative to the QALY.
- Methodological improvements are making HYE estimation more practical.
- Further research and application may re-establish HYE in health technology assessment.
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