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Multiple bilateral spinal nerve root calcifications in Charcot-Marie-Tooth disease
P R Bolos1, M Aribandi, W F Hess
1Department of Radiology, Geisinger Medical Center, Danville, Pennsylvania 17822, USA. prbolos@geisinger.edu
Journal of Medical Imaging and Radiation Oncology
|June 17, 2009
Summary
Charcot-Marie-Tooth disease can present with unusual calcifications. Researchers found multiple, symmetrical calcifications on cervical nerve roots, a previously undescribed feature.
Area of Science:
- Neurology
- Radiology
- Genetics
Background:
- Charcot-Marie-Tooth disease is a group of inherited disorders.
- It affects peripheral nerves, causing muscle weakness and sensory loss.
Observation:
- A patient with Charcot-Marie-Tooth disease exhibited unusual imaging findings.
- Multiple, bilateral, and symmetrical calcifications were observed on the cervical nerve roots.
Findings:
- This specific pattern of nerve root calcification has not been previously reported in association with Charcot-Marie-Tooth disease.
- The calcifications were bilateral and symmetrical along the cervical nerve roots.
Implications:
- These calcifications may represent a novel imaging biomarker for Charcot-Marie-Tooth disease.
- This finding could aid in the diagnosis of this hereditary motor and sensory neuropathy.
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