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In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium
Published on: May 6, 2018
[The surgeon and anti-angiogenics]
1INSERM U965, Institut des Vaisseaux et du Sang, Hôpital Lariboisière, Université Paris-Diderot/Paris VII, 8 rue Guy Patin, 75475 Paris Cedex 10, France. marc.pocard@1rb.aphp.fr
Journal De La Societe De Biologie
|June 17, 2009
Summary
Surgeons need to understand angiogenesis in wound healing and use anti-angiogenics for better surgical outcomes. Current strategies lack daily biological indicators for tissue activity and predicting tumor response.
Area of Science:
- Vascular biology and surgical oncology.
Background:
- Angiogenesis, the formation of new blood vessels, is crucial for wound healing.
- Anti-angiogenic therapies can alter clinical situations and improve surgical outcomes for potentially ineffective procedures.
Purpose of the Study:
- To highlight the importance of angiogenesis in surgery.
- To emphasize the need for biological indicators to guide anti-angiogenic strategies.
Main Methods:
- This study reviews the role of angiogenesis and anti-angiogenics in surgical contexts.
Main Results:
- Current anti-angiogenic strategies lack reliable daily biological indicators for tissue activity.
- There are no established indicators to predict tumor sensitivity to anti-angiogenic treatments.
Conclusions:
- Effective clinical application of anti-angiogenics in surgery requires the development of new biological monitoring tools.
- Predictive markers for anti-angiogenic therapy efficacy are essential for optimizing surgical treatments.
