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Related Concept Videos

Regulation of Expression at Multiple Steps01:23

Regulation of Expression at Multiple Steps

The gene expression in cells is regulated at different stages: (i) transcription, (ii) RNA processing, (iii) RNA localization, and (iv) translation. Transcriptional regulation is mediated by regulatory proteins such as transcription factors, activators, or repressors—these control gene expression by initiating or inhibiting the transcription of genes. Once a precursor or pre-mRNA is produced, it undergoes post-transcriptional modification, including 5' capping, splicing, and the addition of a...
Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
Regulation of Expression Occurs at Multiple Steps02:24

Regulation of Expression Occurs at Multiple Steps

Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...

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Updated: Jun 22, 2026

Chicken Recombinant Limbs Assay to Understand Morphogenesis, Patterning, and Early Steps in Cell Differentiation
08:08

Chicken Recombinant Limbs Assay to Understand Morphogenesis, Patterning, and Early Steps in Cell Differentiation

Published on: January 12, 2022

Gene expression patterns associated with chicken jejunal development.

Dirkjan Schokker1, Arjan J W Hoekman, Mari A Smits

  • 1Animal Breeding and Genomics Centre, Wageningen UR, Lelystad, The Netherlands. D.Schokker@gmail.com

Developmental and Comparative Immunology
|June 17, 2009
PubMed
Summary
This summary is machine-generated.

This study reveals distinct gene expression patterns during chicken jejunal development. Transcriptomics offers detailed insights into the morphological, functional, and immunological changes occurring post-hatch.

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Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay
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11:48

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Area of Science:

  • Animal Science
  • Genomics
  • Developmental Biology

Background:

  • Jejunal development is a complex process involving spatio-temporal changes.
  • Understanding the molecular mechanisms driving this development is crucial for poultry science.

Purpose of the Study:

  • To investigate jejunal development at the transcriptomic level in chickens.
  • To identify gene expression patterns correlating with morphological, functional, and immunological development.

Main Methods:

  • Microarray analysis was performed on jejunal tissues from chickens aged 1 to 21 days.
  • Gene expression data were clustered to identify patterns and functional groups.

Main Results:

  • Nine distinct gene expression clusters were identified.
  • Genes related to morphological and functional development showed high expression post-hatch, decreasing over time.
  • Immunological development was characterized by three temporal phases based on gene expression: innate response, differentiation, and maturation.

Conclusions:

  • Specific gene expression patterns correlate with jejunal morphological, functional, and immunological development.
  • Transcriptomic analysis provides a detailed understanding of the biological processes underlying jejunal development.