Related Experiment Video
Updated: Jun 22, 2026

A Microscopic 2,3,5-Triphenyltetrazolium Chloride Assay for Accurate and Reliable Analysis of Myocardial Injury
Published on: November 28, 2025
Recurrent Takotsubo cardiomyopathy
Christopher D Maroules1, Nelle A Linz, Gilbert E Boswell
1Department of Internal Medicine, Naval Medical Center San Diego, San Diego, CA 92134-5000, USA.
Insights
This study details a case of Takotsubo Cardiomyopathy in a 71-year-old woman. Advanced imaging confirmed normal coronary arteries and characteristic left ventricular dysfunction.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Takotsubo Cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, is a transient heart condition.
- It is often triggered by emotional or physical stress and can mimic myocardial infarction.
Observation:
- A 71-year-old woman presented with symptoms suggestive of cardiac distress.
- Diagnostic workup included dual-source multidetector CT, cardiac MRI, and echocardiography.
Findings:
- CT angiography revealed normal coronary arteries, ruling out obstructive coronary artery disease.
- Cardiac MRI and echocardiography demonstrated classic findings of TTC: mid left ventricular hypokinesis and apical akinesis.
- Three-dimensional imaging provided a detailed view of the abnormal ventricular wall motion.
Implications:
- This case highlights the utility of multimodality imaging in diagnosing Takotsubo Cardiomyopathy.
- Accurate diagnosis is crucial to differentiate TTC from acute coronary syndromes, guiding appropriate management and preventing unnecessary invasive procedures.
Abstract:
We present the case of a 71-year-old woman with Takotsubo Cardiomyopathy as imaged with a dual source multidetector CT, MRI, and follow-up echocardiography. This demonstrates normal coronary arteries by use of CT angiography, and a 3D perspective of abnormal mid left ventricular hypokinesis and apical left ventricular akinesis.
Related Concept Videos
Cardiomyopathy I: Introduction and Classification
Cardiomyopathy IV: Restrictive Cardiomyopathy
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Myocarditis II: Clinical Features and Diagnostic Tests
