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Updated: Jun 22, 2026

Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional (3D) Model
Published on: June 11, 2014
Diffusion-drift modeling of a growing breast cancerous cell
Ahmed M Hassan1, Magda El-Shenawee
1Department of Electrical Engineering, University of Arkansas, Fayetteville, AR 72701, USA. amhassan@uark.edu
Abstract:
This paper presents a 2-D model to calculate the electric current densities and the biopotential differences generated due to a breast cancerous cell during the hyperpolarization of the G1/synthesis (G1/S) transition. The proposed model is based on semiconductor diffusion-drift analysis, and aims to understand the biophysics associated with growing breast cancerous cells. The effect of the duration of the G1/S transition, and the diffusivity and the mobility of the cancerous cell boundary is investigated. The results show that shorter G1/S transition durations, and higher diffusivity and mobility at the cell boundary provide higher magnitude of the electric signals.
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