Molecular identification by generating coherence between molecular normal modes using stimulated Raman scattering
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Updated: Jun 22, 2026

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
Published on: July 25, 2022
Daniel L Marks1, Joseph B Geddes Iii, Stephen A Boppart
1Beckman Institute for Advanced Science and Technology, Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Abstract:
We propose a method of driving the vibrations of normal modes of a target molecule into coherence using stimulated Raman scattering. In concert many vibrations can produce a larger anti-Stokes signal than a single vibration. The same illumination does not drive other molecules to have coherent vibrations so that these molecules produce a weaker signal. We investigate how target and confounder molecules can be distinguished by pulses that drive many vibrations coherently, which has applications in coherent Raman microspectroscopy.
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