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Updated: Jun 22, 2026
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Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
Published on: August 1, 2025
Endoscopic hemorrhoidal sclerotherapy using 50% dextrose water: a preliminary report
Olusegun I Alatise1, Olu A Arigbabu, Oladejo O Lawal
1Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Nigeria. segunalatishe@yahoo.co.uk
Summary
This study shows 50% dextrose water effectively treated bleeding hemorrhoids in Nigeria. All patients experienced symptom resolution with no complications, offering a safe and accessible treatment option.
Area of Science:
- Gastroenterology
- Colorectal Surgery
Background:
- Injection sclerotherapy is a key treatment for bleeding hemorrhoids.
- Commonly used sclerosants are inaccessible or costly in Nigeria.
Purpose of the Study:
- To evaluate 50% dextrose water as a safe and effective sclerosant for bleeding internal hemorrhoids.
- To assess the response, tolerance, and complications of this treatment modality.
Main Methods:
- Prospective evaluation of 40 adult patients with bleeding hemorrhoids.
- Treatment involved injection sclerotherapy using 50% dextrose water.
- Patients were monitored for symptom resolution and adverse events over 2 to 12 months.
Main Results:
- Complete cessation of bleeding after a single injection in all 40 patients.
- No patient required repeat procedures.
- No complications were observed during the follow-up period.
Conclusions:
- 50% dextrose water is a simple, safe, and effective sclerosant for treating bleeding internal hemorrhoids.
- This modality offers a viable alternative in resource-limited settings like Nigeria.
