Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photon-Counting Detector CT-Based Virtual Monoenergetic Imaging With Metal Artifact Reduction for Endodontic Diagnostics.

International dental journal·2026
Same author

Optimization of dental implant imaging using photon-counting detector computed tomography in oral and maxillofacial surgery: an ex vivo study.

European radiology experimental·2026
Same author

Virtual monoenergetic imaging for metal artifact reduction in dental implant surgery using photon-counting detector computed tomography.

Imaging science in dentistry·2026
Same author

Postoperative MRI in cranio-maxillofacial and oral reconstruction: A prospective comparative pilot study on artifact reduction.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery·2026
Same author

[Segmental odontomaxillary dysplasia - A case report].

Swiss dental journal·2026
Same author

Photon-counting detector vs. cone-beam CT in endodontics: a study of simulated endodontic conditions, treatments, and associated complications.

BMC oral health·2026

Related Experiment Video

Updated: Jun 22, 2026

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
11:51

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

Increased bone formation around coated implants.

Bernd Stadlinger1, Susanne Bierbaum, Silke Grimmer

  • 1Department of Oral and Maxillofacial Surgery, Faculty of Medicine, University of Technology Dresden, Dresden, Germany. stadlinger@gmx.de

Journal of Clinical Periodontology
|June 18, 2009
PubMed
Summary
This summary is machine-generated.

Coating titanium implants with collagen and chondroitin sulphate (CS) significantly enhanced bone formation after one month. This biomaterial coating shows promise for improving dental implant osseointegration and stability.

More Related Videos

Oral Biofilm Formation on Different Materials for Dental Implants
11:19

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Related Experiment Videos

Last Updated: Jun 22, 2026

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
11:51

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

Oral Biofilm Formation on Different Materials for Dental Implants
11:19

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Area of Science:

  • Biomaterials Science
  • Dental Implantology
  • Tissue Engineering

Background:

  • Titanium implants are widely used in dentistry.
  • Enhancing implant osseointegration and stability is crucial for successful outcomes.
  • Surface modifications can influence bone healing around implants.

Purpose of the Study:

  • To evaluate the effect of coating sandblasted acid-etched titanium implants with collagen and chondroitin sulphate (CS) on bone formation and implant stability.
  • To compare low-dose (CS1) and high-dose (CS2) CS coatings against uncoated controls.

Main Methods:

  • Three implant surface groups: control (sandblasted acid-etched), CS1 (low-dose CS), and CS2 (high-dose CS).
  • Sixty implants placed in minipig mandibles.
  • Assessment of bone-implant contact (BIC), relative peri-implant bone-volume density (rBVD), and resonance frequency analysis (RFA) at 1 and 2 months.

Main Results:

  • After 1 month, CS-coated implants showed significantly higher BIC than controls.
  • At 2 months, BIC increased for all groups, with no significant differences.
  • rBVD increased for coated implants at 2 months; RFA values showed no significant differences between groups.

Conclusions:

  • Collagen/CS coating positively influences bone formation at 1 month.
  • The findings suggest potential benefits of CS coating for early osseointegration.