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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

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Related Experiment Video

Updated: Jun 22, 2026

Measurement of Spatial Stability in Precision Grip
09:36

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Published on: June 4, 2020

Grip force control in individuals with multiple sclerosis.

Veena Iyengar1, Marcio J Santos, Michael Ko

  • 1Department of Physical Therapy, University of Illinois at Chicago.

Neurorehabilitation and Neural Repair
|June 18, 2009
PubMed
Summary
This summary is machine-generated.

Individuals with multiple sclerosis (MS) use excessive grip force and exhibit longer time lags during daily tasks. This may lead to fatigue and overuse injuries, requiring adjustments in rehabilitation protocols for the MS population.

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Area of Science:

  • Neurology
  • Biomechanics
  • Rehabilitation Science

Background:

  • Grip force regulation is crucial for daily activities.
  • Understanding grip control in multiple sclerosis (MS) is limited.

Purpose of the Study:

  • To investigate grip force control in individuals with MS during functional tasks.

Main Methods:

  • Compared grip force control in 9 individuals with MS and 9 healthy controls.
  • Assessed tasks mimicking drinking and object manipulation.
  • Recorded grip forces, object acceleration, force ratio, and time lag.

Main Results:

  • Individuals with MS applied significantly higher peak grip force and force ratio.
  • A longer time lag between grip and load forces was observed in the MS group.
  • These differences were consistent for both hands and tasks.

Conclusions:

  • Excessive grip force in MS may increase fatigue and risk of overuse injuries.
  • Rehabilitation strategies for MS should consider altered grip force application.
  • Further research may inform targeted interventions for improved functional performance.