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[Quantitative relationships of structure and antimicrobial activity in azole-containing chemotherapeutics]
Abstract:
Several novel azole-containing compounds belonging to condensed heterocycles were studied in vitro within the program of screening antimicrobial substances. Changes in the activity of the compounds against 8 representatives of the microbial genera dependent on the chemical structure were followed up. The changes in the structure referred to the radicals at positions 1 and 3.