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Updated: Jun 22, 2026

Colorimetric Assessment of Deiodinase 1 Activity in Human Liver Microsomes Using the Sandell-Kolthoff Reaction
Published on: April 10, 2026
[Urinary iodine excretion in German adults in 2005 meets WHO target]
Rainer Hampel1, Gundolf Bennöhr, Ansgar Gordalla
1Abteilung für Endokrinologie und Stoffwechselkrankheiten, Klinik für Innere Medizin, Universität Rostock, Rostock, Germany. rainer.hampel@med.uni-rostock.de
Background:
Recent regional and Germany-wide investigations have shown that the abolition of the requirement to declare iodine in foodstuffs and the greater emphasis on information about goitre prevention led to an increase in urinary iodine excretion in German schoolchildren. There was also a decrease in thyroid size and goitre prevalence in children. No up-to-date results in adults for the whole of Germany are available.
Methods:
In 2005, the authors examined the urinary iodine excretion in the spontaneous morning urine of 1,538 healthy adults in 357 places from all over Germany. The iodine was measured by the cer-arsenite method.
Results:
The median iodine excretion amounted to 132 microg/l. There were no significant differences between age groups, sexes or regions. 64% had no iodine deficiency (> or = 100 microg/l). In 23% the deficiency was slight (50-99 microg/l), in 10% moderate (20-49 microg/l), and in 3% there was severe iodine deficiency (< 20 microg/l). 29% excreted > 200 microg iodide/l urine.
Conclusion:
According to the WHO (World Health Organization) guidelines, there is no longer an iodine deficiency in German adults.
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