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Updated: Jun 22, 2026
Manual Segmentation of the Human Choroid Plexus Using Brain MRI
Published on: December 15, 2023
Rapid evolution of a choroid plexus papilloma in an infant
Aimun A B Jamjoom1, Momen A Sharab, Abdulhakim B Jamjoom
1Section of Neurosurgery, King Khalid National Guards Hospital, Jeddah 21423, Saudi Arabia.
Insights
Choroid plexus papilloma (CPP) can grow rapidly in infants. This case study documents a CPP undetected on MRI that grew significantly in just five months, highlighting its rapid growth potential.
Area of Science:
- Pediatric Neurosurgery
- Developmental Biology
- Oncology
Background:
- Choroid plexus papilloma (CPP) is a rare brain tumor typically diagnosed in children under two years old or prenatally.
- While large CPPs are common in infants, data on their growth rate during infancy is scarce.
- Surgical excision is the standard treatment, often performed without delay.
Observation:
- A preterm infant presented with a choroid plexus papilloma.
- The tumor was initially undetected on magnetic resonance imaging (MRI).
- Over a five-month period, the CPP exhibited significant growth to a large size.
Findings:
- This case provides rare documentation of the rapid growth potential of choroid plexus papilloma in infancy.
- The observed growth rate challenges assumptions about the typical progression of this benign tumor in very young patients.
- The study discusses potential explanations for this accelerated tumor growth.
Implications:
- Understanding the rapid growth potential of CPP in infants is crucial for timely diagnosis and management.
- This case may inform surgical planning and follow-up strategies for pediatric CPP.
- Further research into the factors influencing CPP growth in infancy is warranted.
Abstract:
Choroid plexus papilloma (CPP) is primarily found in children less than 2 years of age but can also be diagnosed prenatally. The presentation of a large CPP during infancy is not uncommon and surgical excision is usually recommended without delays. As a result, information about the growth rate of CPP during infancy is lacking. We report a preterm infant who presented with a choroid plexus papilloma that grew from being undetected on MRI to reaching a large size in 5 months. The case is unique in that it provides documentation of the rapid growth potential of this benign tumour in infancy. A possible explanation for this occurrence is discussed.
