A rare neural tube defect: a report of eight cases in Pakistan

Iniencephaly is a rare congenital malformation of central nervous system and axial skeleton. Eight cases were seen in the Department of Obstetrics and Gynaecology, Jinnah Post-Graduate Medical Centre over a 12 month period constituting 0.1% of all deliveries conducted, the estimated frequency being 1: 850 deliveries. The purpose of this paper is to describe our cases and to report several considerations which might influence the antenatal diagnosis of this rare anomaly.