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Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique
Published on: September 20, 2011
Novel amphiphilic hyperbranched poly (amine-ester) copolymers nanoparticles as protein drug delivery
Ming Jiang1, Tiewei Wang, Qing Xu
1National Center for Nanoscience and Technology, Beijing, China.
Mini Reviews in Medicinal Chemistry
|June 19, 2009
Abstract:
Novel amphiphilic protein-loaded hyperbranched poly (amine-ester) copolymers nanoparticles were fabricated by double emulsion (DE) and nanoprecipitation (NP) methods. Encapsulation efficiency (EE) of nanoparticles to Bovine serum albumin (BSA) could reach 97.8% at BSA (0.01 g/ml), internal phase volume (0.5 ml), copolymer weight (50mg), and PVA concentration (4%, w/v) condition.
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