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HRT-3 Moorfields reference plane: effect on rim area repeatability and identification of progression.
R Asaoka1, N G Strouthidis, V Kappou
1NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London EC1V 2PD, UK.
The British Journal of Ophthalmology
|June 19, 2009
Summary
The Moorfields Reference Plane improves Heidelberg Retina Tomograph (HRT) rim area repeatability and detects more glaucoma progression than the Standard RP. This method enhances glaucoma monitoring by identifying change more effectively.
Area of Science:
- Ophthalmology
- Medical Imaging
- Glaucoma Research
Background:
- Heidelberg Retina Tomograph (HRT) is crucial for glaucoma diagnosis.
- Accurate rim area measurement is vital for detecting glaucoma progression.
- Standard Reference Planes (RP) in HRT imaging have limitations in repeatability.
Purpose of the Study:
- To evaluate the Moorfields Reference Plane's impact on HRT rim area repeatability.
- To assess if the Moorfields RP improves the detection of glaucoma progression.
- To compare the Moorfields RP with Standard and 320 RPs.
Main Methods:
- Applied Moorfields RP to HRT test-retest data to calculate rim area repeatability coefficients.
- Compared repeatability coefficients of Moorfields, Standard, and 320 RPs.
- Analyzed HRT images from 198 ocular hypertensives over 6 years for progression using event analysis.
Main Results:
- Moorfields RP enhanced rim area repeatability compared to the Standard RP.
- Repeatability was comparable between Moorfields RP and 320 RP.
- Moorfields RP identified progression in 40% of cases versus 28% for 320 RP, with higher concurrent field progression detection.
Conclusions:
- The Moorfields RP offers improved detection of glaucomatous change compared to the 320 RP.
- While rim area repeatability is similar, the Moorfields RP is superior for identifying progression.
- This novel RP enhances the sensitivity of HRT in glaucoma monitoring.
