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Updated: Jun 22, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Therapeutic hypothermia for acute myocardial infarction: past, present, and future
William Parham1, Kalie Edelstein, Barbara Unger
1Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA. William.M.Parham@allina.com
Abstract:
Therapeutic hypothermia has been shown in randomized clinical trials to improve neurologic outcomes following cardiac arrest. Whether therapeutic hypothermia improves important outcomes after acute myocardial infarction is an area of active research. Here we review recent experimental and clinical data that examine whether therapeutic hypothermia can improve functional outcomes or mortality rate in acute myocardial infarction. We conclude that the available clinical evidence does not support therapeutic hypothermia as standard therapy for acute myocardial infarction.
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