Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Alterations in Blood Pressure

Alterations in Blood Pressure

Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...

Special considerations while measuring blood pressure

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Pre-Procedural Guidelines for Assessing Blood Pressure

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Fatty acid signatures of duck breast meat from three varieties.

Poultry science·2026

Same author

Nek1 defines a branch of centriolar microtubule length control parallel to CP110-Cep97.

Nature communications·2026

Same author

Evaluation of cardiovascular fall risk assessment and managment in Dutch fall clinics comparing current practice to guideline recommendations.

European geriatric medicine·2026

Same author

Clusters of vascular aging manifestations predict incident cardiovascular events in the community.

Nature communications·2026

Same author

Efficacy of binders on sequestering per- and polyfluoroalkyl substances under in vitro ruminal conditions.

Journal of dairy science·2025

Same author

Response to letter to the editor, regarding "Falls prevention in community-dwelling older adults and implementation of world falls guidelines: a call for action across Europe".

European geriatric medicine·2025

Search research articles

Related Experiment Video

Updated: Jun 22, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

Orthostatic hypotension in older persons: a diagnostic algorithm.

T Krecinic¹, F Mattace-Raso, N Van Der Velde

¹Section of Geriatric Medicine, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

The Journal of Nutrition, Health & Aging

|June 19, 2009

Summary

This summary is machine-generated.

Orthostatic hypotension (OH) is common in older adults and often has multiple causes. A diagnostic approach focusing on frequent causes is recommended for suspected cases.

Related Experiment Videos

Last Updated: Jun 22, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

Area of Science:

Gerontology
Cardiovascular Medicine
Neurology

Background:

Orthostatic hypotension (OH) is a prevalent condition in the elderly population.
OH often presents with multifactorial etiologies, complicating diagnosis and management.
Identifying the underlying causes of OH is crucial for effective treatment in older individuals.

Purpose of the Study:

To present a clinical algorithm for the diagnostic work-up of orthostatic hypotension in older persons.
To guide healthcare providers in systematically evaluating the most common causes of OH.
To provide a practical tool for improving the diagnostic process of orthostatic hypotension.

Main Methods:

The study proposes a diagnostic algorithm based on the prevalence of OH causes in the elderly.
The algorithm emphasizes initial investigation of the most frequent etiologies.
This approach aims to streamline the diagnostic pathway for suspected orthostatic hypotension.

Main Results:

The proposed clinical algorithm focuses on prevalent causes of orthostatic hypotension.
This systematic approach aids in efficiently diagnosing the condition.
The algorithm serves as a valuable tool for clinicians managing elderly patients with OH.

Conclusions:

Orthostatic hypotension is a frequent and multifactorial issue in older adults.
A diagnostic strategy prioritizing common causes is essential.
The presented clinical algorithm can aid in the diagnostic process for orthostatic hypotension.