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Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
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A uniform residual tumor (R) classification: integration of the R classification and the circumferential margin
Christian Wittekind1, Carolyn Compton, Phil Quirke
1Institute of Pathology, University Clinic Leipzig, Leipzig, Germany. wittc@medizin.uni-leipzig.de
Background:
Since the introduction of the TNM residual tumor (R) classification, the involvement of resection margins has been defined either as a microscopic (R1) or a macroscopic (R2) demonstration of tumor directly at the resection margin ("tumor transected").
Methods:
The recognition of the importance of the circumferential resection margin (CRM) in patients with rectal cancer patients raises the need for an alternative definition of resection margin involvement, namely, the importance of delineating tumor with a minimal distance from the CRM of
Results:
To avoid confusion by different definitions, the authors proposed including the minimal distance between tumor and resection margin into the current R classification.
Conclusions:
By using the proposed expanded classification, comparisons of new data with previous publications will be possible.
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