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Updated: Jun 22, 2026

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DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
Published on: February 27, 2014
Abstract:
Two teams recently published reports on neuroleptic-induced ischaemic colitis, a rare but potentially serious adverse effect. So-called atypical neuroleptics have also been implicated.
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Introduction
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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