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Prevalence of anti-thyroid antibodies in patients with primary thyroid disorders
1Department of Human Pathology, College of Health Sciences, University of Nairobi, P.O. Box 19676-00202, Nairobi, Kenya.
Objective:
To determine prevalence of thyroid antimicrosomal and antithyroglobulin antibodies among patients with primary thyroid disorders.
Design:
Descriptive cross-sectional study.
Setting:
Kenyatta National Hospital, July 2003 to August 2004.
Results:
Antimicrosomal antibodies (anti-TPOAbs) were detected in 51.4% of all the patients while 36.1% tested positive for the antithyroglobulin antibodies (anti- TgAbs). Among the hyperthyroid patients, anti-TPOAbs and anti-TgAbs were in 50.8% and 33% respectively while 53.3% and 46.7% of the hypothyroid patients tested positive for anti-TPOAbs and anti-TgAbs respectively. Most of the patients who showed positivity for anti-TgAbs (88.5%) also tested positive for anti-TPOAbs.
Conclusion:
More than half of the patients with primary thyroid disorders show presence of autoimmune thyroid markers, with anti TPO antibodies being more prevalent.
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