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Related Experiment Video

Updated: Jun 22, 2026

Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research
08:23

Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research

Published on: August 31, 2013

Insights in Bartonella host specificity.

Muriel Vayssier-Taussat1, Danielle Le Rhun, Sarah Bonnet

  • 1UMR Bipar, Afssa 23 rue du Général de Gaulle, 94 700 Maisons-Alfort, France. mvayssier@vet-alfort.fr

Annals of the New York Academy of Sciences
|June 23, 2009
PubMed
Summary

Bartonella bacteria are emerging intracellular pathogens causing long-lasting infections in many mammals, including humans. This review explores the mechanisms behind Bartonella species

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Veterinary Medicine

Background:

  • Bartonella are emerging gram-negative, intracellular bacteria.
  • They cause long-lasting intraerythrocytic bacteremia in reservoir hosts.
  • The genus has expanded to 24 species, with half linked to human disease.

Purpose of the Study:

  • To review the diversity and host specificity of Bartonella species.
  • To discuss potential mechanisms explaining host specificity.

Main Methods:

  • Literature review of Bartonella research.
  • Analysis of host-pathogen interactions.

Main Results:

  • Bartonella infect a wide range of mammals, from bats to humans.

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  • Each Bartonella species exhibits specificity for a limited number of animal hosts.
  • Over half of the 24 described species are associated with human disease.

    • Conclusions:

    • Bartonella adaptation to diverse mammals has led to significant host specificity.
    • Understanding these specificity mechanisms is crucial for disease control.