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Related Concept Videos

The Phragmoplast01:59

The Phragmoplast

Cell division is essential for organismal growth and development. In animal cells, the central spindle and its associated proteins form the midbody, a structure that has an essential role in cytokinesis. In plants, the central spindle, along with the microtubules, actin, and other cell components, matures into the phragmoplast, which is necessary for cytokinesis. Unlike the stationary midbody, the phragmoplast expands centrifugally, eventually leading to the formation of the new cell wall.
The...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...

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Related Experiment Videos

A phyllodes tumor in a child.

Chiara Adriana Pistolese1, Ilaria Tanga, Elsa Cossu

  • 1Department of Diagnostical Imaging and Interventional Radiology, University of Rome Tor Vergata, Rome 00133, Italy.

Journal of Pediatric and Adolescent Gynecology
|June 23, 2009
PubMed
Summary

Phyllodes tumor of the breast, a rare breast neoplasm, can occur in young women. This case highlights an 11-year-old girl presenting with nipple discharge, an unusual symptom for this condition.

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Area of Science:

  • Oncology
  • Radiology
  • Pediatric Surgery

Background:

  • Phyllodes tumors are rare breast neoplasms, typically presenting as palpable masses.
  • They are uncommon in adolescent girls and young women.

Observation:

  • An 11-year-old adolescent girl presented with non-hematic nipple discharge.
  • Diagnostic imaging included ultrasound, mammography, and magnetic resonance imaging.

Findings:

  • Histological examination confirmed a phyllodes tumor.
  • The case presents an unusual clinical manifestation of this rare breast neoplasm.

Implications:

  • This case underscores the importance of considering rare diagnoses in pediatric patients with atypical symptoms.
  • Understanding the varied clinical presentations of phyllodes tumors is crucial for timely diagnosis and management in young individuals.