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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

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Related Experiment Video

Updated: Jun 22, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Self-tonometry in glaucoma management--past, present and future.

Steve Y-W Liang1, Graham A Lee, David Shields

  • 1City Eye Centre, Brisbane, Queensland, Australia.

Survey of Ophthalmology
|June 23, 2009
PubMed
Summary

Patient self-tonometry offers a promising solution for monitoring intraocular pressure, crucial for managing glaucoma. This approach helps track daily eye pressure fluctuations and medication effectiveness, unlike traditional office measurements.

Related Experiment Videos

Last Updated: Jun 22, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Glaucoma is a leading cause of irreversible blindness globally.
  • Current intraocular pressure (IOP) measurements in clinical settings are insufficient for detecting diurnal variations or treatment effects.

Purpose of the Study:

  • To review the historical development of self-tonometry devices.
  • To present emerging technologies for future patient-directed IOP monitoring.

Main Methods:

  • Literature review of self-tonometry device history.
  • Analysis of current and future self-tonometry technologies.

Main Results:

  • Traditional IOP measurements do not capture critical diurnal fluctuations or medication adherence.
  • Patient-directed self-tonometry allows for comprehensive, real-time IOP data collection.

Conclusions:

  • Self-tonometry is essential for effective glaucoma management by providing continuous IOP data.
  • Future technologies in self-tonometry promise improved glaucoma diagnosis and patient care.