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Updated: Jun 22, 2026
A Simple Method for Automated Solid Phase Extraction of Water Samples for Immunological Analysis of Small Pollutants
Published on: January 1, 2016
Preparation and evaluation of molecularly imprinted solid-phase microextraction fibers for selective extraction of
Feng Tan1, Hongxia Zhao, Xiaona Li
1Key Laboratory of Industrial Ecology and Environmental Engineering, Ministry of Education, School of Environmental & Biological Science & Technology, Dalian University of Technology, Dalian, Liaoning 116024, China. tanfengquan@yahoo.com.cn
Abstract:
Molecular imprinted polymer (MIP) as solid-phase microextraction (SPME) fibers coating has gained great attention in recent years. In this study, a simple preparation approach for bisphenol A (BPA) MIP coating with controlled thickness on fused-silica capillaries was developed. A capillary was inserted into a larger bore capillary to form a sleeve as mold. The prepolymer solution containing the template BPA was introduced into the interspace between the two capillaries for polymerization under photoirradiation. The larger bore capillary was removed away after the polymerization, and MIP coating with certain thickness on the surface of the inserted capillary was obtained. SPME conditions based on the MIP-coated fibers were optimized, and the extraction performance of the fibers with different thickness coating was compared. Finally, the MIP fibers were used for selective extraction of BPA spiked in tap water, human urine, and milk samples. The average recoveries of spiked BPA in the three samples were 92.5%, 81.6%, and 87.5%, respectively. The present analytical performance is not up to par for applicability to real environmental matrices. Further improvement will be necessary for analysis of real complex samples.
