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Updated: Jun 22, 2026

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Published on: February 22, 2018
Mechanisms of focal ventricular tachycardia in humans
Steven M Markowitz1, Bruce B Lerman
1Department of Medicine, Division of Cardiology, Weill Cornell Medical College, New York, New York 10021, USA. smarkow@med.cornell.edu
Abstract:
In classifying ventricular arrhythmias, a fundamental distinction is made between focal and macroreentrant mechanisms. Focal arrhythmias demonstrate early activation at a particular site with centrifugal spread of the impulse from this site of origin. In contrast, macroreentrant rhythms involve contiguous but spatially distributed areas of activation. Despite advances in multielectrode and electroanatomical mapping, the distinction of a focal from a macroreentrant mechanism is sometimes problematic.
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