Amyloid-beta, tau, and dementia.

Akihiko Takashima1

  • 1Laboratory for Alzheimer's Disease, RIKEN Brain Science Institute, Wako, Saitama, Japan. kenneth@brain.riken.go.jp

Summary

Alzheimer's disease (AD) involves brain changes like amyloid-beta and neurofibrillary tangles. This review suggests that brain aging, marked by tangles in the entorhinal cortex, may be necessary for AD to develop.

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