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End-stage renal disease in Taiwan: a case-control study
Su-Ying Tsai1, Hung-Fu Tseng, Hsiu-Fen Tan
1Department of Health Management, I-Shou University, Yanchao Township, Kaohsiung County, Taiwan (R.O.C.). sytsai@isu.edu.tw
Journal of Epidemiology
|June 23, 2009
Summary
Low socioeconomic status, hypertension, diabetes, and herbal remedies increase end-stage renal disease (ESRD) risk in Taiwan. Multivitamin use may decrease ESRD risk.
Area of Science:
- Nephrology
- Epidemiology
- Public Health
Background:
- Taiwan faces the world's highest incidence of end-stage renal disease (ESRD).
- Epidemiologic features of ESRD in Taiwan remain under-investigated.
- This study aimed to identify risk factors for ESRD in the Taiwanese population.
Purpose of the Study:
- To evaluate the association between various putative risk factors and end-stage renal disease (ESRD).
- To identify key demographic, clinical, and lifestyle factors contributing to ESRD incidence in Taiwan.
Main Methods:
- A case-control study involving 200 newly diagnosed ESRD patients and 200 controls.
- Data collected via structured questionnaire on socioeconomic status, medical history, lifestyle, and supplement use.
- Information gathered retrospectively for factors present 5 years prior to disease onset.
Main Results:
- Low socioeconomic status (education and income) significantly predicted ESRD.
- History of hypertension and diabetes were strong predictors of ESRD.
- Regular use of folk remedies/Chinese herbs showed a high odds ratio for ESRD, while multivitamin use showed a decreased risk.
Conclusions:
- Low socioeconomic status, hypertension, diabetes, and use of folk remedies are significant ESRD risk factors.
- Regular multivitamin supplementation demonstrated a protective association with ESRD.
- Findings highlight modifiable and non-modifiable factors influencing ESRD in Taiwan.
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