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Related Experiment Video

Updated: Jun 22, 2026

Effect of Artificial Tear Formulations on the Metabolic Activity of Human Corneal Epithelial Cells after Exposure to Desiccation

Effect of Artificial Tear Formulations on the Metabolic Activity of Human Corneal Epithelial Cells after Exposure to Desiccation

Published on: May 2, 2020

Are the new moisturizers more effective?

P Chris Anderson¹, James G Dinulos

¹Section of Dermatology, Dartmouth-Hitchcock Medical Center Dartmouth Medical School Lebanon, Lebanon, NH 03756, USA. pchris@hitchcock.org

Current Opinion in Pediatrics

|June 23, 2009

Summary

Moisturizers, especially those containing ceramides, are crucial for managing atopic dermatitis. These products improve skin barrier function and may reduce the need for topical steroids in daily skin care.

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Area of Science:

Dermatology
Skin barrier function
Atopic dermatitis management

Background:

Atopic dermatitis (eczema) involves impaired skin barrier function.
Stratum corneum lipid deficiency, particularly ceramides, is noted in affected skin.
Daily moisturization is a cornerstone of atopic dermatitis management.

Purpose of the Study:

To review the role of moisturizers in skin care for healthy skin and atopic dermatitis.
To evaluate the efficacy of newer moisturizer formulations, particularly those containing ceramides.

Main Methods:

Review of recent scientific literature on moisturizers and atopic dermatitis.
Analysis of the composition and efficacy of novel ceramide-containing products.
Comparison of ceramide-based moisturizers with traditional formulations.

Main Results:

Atopic skin shows a deficiency in ceramides, essential lipids for the stratum corneum.
Newer topical products containing ceramides demonstrate moderate efficacy improvements over conventional moisturizers.
Ceramide-containing moisturizers may help reduce reliance on topical steroids.

Conclusions:

Moisturizers are essential for nearly all patients with atopic dermatitis.
Daily use of moisturizers can help maintain disease control and potentially reduce topical steroid requirements.
Physician recommendations for specific, effective moisturizer products, especially those with ceramides, are needed due to consumer choice overwhelm.