Acute fibrinous and organizing pneumonia following hematopoietic stem cell transplantation
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Updated: Jun 22, 2026

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Published on: October 11, 2024
Sang Min Lee1, Jae-Jung Park, Sun Hee Sung
1Department of Internal Medicine, Inje University College of Medicine, Busan, Korea.
Abstract:
A 60-year-old man presented with cough, sputum, and dyspnea. He had a history of acute myeloid leukemia and hematopoietic stem cell transplantation with chronic renal failure. Chest CT scans showed miliary nodules and patchy consolidations. Histological examination revealed numerous fibrin balls within the alveoli and thickening of the alveolar septum, both of which are typical pathological features of acute fibrinous and organizing pneumonia (AFOP). We report the first case of AFOP following allogeneic hematopoietic stem cell transplantation.
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