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Neurobiology of pain in children: an overview

Alberto Loizzo1, Stefano Loizzo, Anna Capasso

  • 1Istituto Superiore di Sanita', Roma.

The Open Biochemistry Journal
|June 23, 2009
PubMed

Insights

Assessing infant pain is challenging due to subjective experiences and persistent myths. This review explores theories on pain development in newborns and infants, crucial for effective pain management.

Area of Science:

  • Pediatrics
  • Pain Management
  • Neonatology

Background:

  • Pain assessment in newborns and infants is complex due to its subjective nature.
  • Historically, myths about infant pain perception and management hindered adequate care.
  • Misconceptions regarding pain quantification, treatment efficacy, and medication side effects persisted.

Purpose of the Study:

  • To review and describe various theories on pain pathogenesis in pediatric populations.
  • To address the challenges and historical myths surrounding infant pain evaluation.
  • To provide a foundation for understanding pain mechanisms in neonates and infants.

Main Methods:

  • Literature review of existing theories on pain pathogenesis in children.
  • Analysis of historical perspectives and persistent myths in infant pain assessment.
  • Synthesis of current understanding regarding pain perception in neonates and infants.

Main Results:

  • Several myths regarding infant pain perception, assessment, and treatment have historically influenced clinical practice.
  • Understanding pain pathogenesis is critical for accurate assessment and effective management.
  • The subjective nature of pain necessitates robust theoretical frameworks for interpretation.

Conclusions:

  • Overcoming myths and improving pain assessment are vital for infant well-being.
  • A deeper understanding of pain pathogenesis in neonates and infants is essential for advancing clinical practice.
  • This review highlights the need for evidence-based approaches to pediatric pain management.

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