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Related Experiment Video

Updated: Jun 22, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

B I Simon1, A L Zatcoff, J J W Kong

  • 1New Jersey Dental School, USA. simonbi@umdnj.edu

The Open Dentistry Journal
|June 23, 2009
PubMed
Summary
This summary is machine-generated.

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Platelet-rich fibrin matrix (PRFM) significantly enhanced healing in canine extraction sockets compared to bone grafts. PRFM alone promoted faster osseous fill, suggesting its potential as a superior graft for ridge preservation.

Area of Science:

  • Periodontology
  • Regenerative Medicine
  • Biomaterials

Background:

  • Platelet-rich plasma (PRP) shows promise for ridge preservation due to its growth factors.
  • Platelet-rich fibrin matrix (PRFM) is being investigated for enhanced wound healing.
  • Comparing PRFM to traditional bone grafts is crucial for optimizing ridge preservation techniques.

Purpose of the Study:

  • To evaluate the efficacy of PRFM in promoting healing of extraction sockets in a canine model.
  • To compare the healing response of PRFM-treated sites with sites treated with Demineralized Freeze-Dried Bone Allograft (DFDBA) and untreated controls.
  • To assess the potential of PRFM as a standalone graft for ridge preservation.

Main Methods:

  • Four canine extraction sockets were treated with PRFM, PRFM with membrane, DFDBA with membrane, PRFM with DFDBA, or left untreated.
Keywords:
Platelet growth factorsguided bone regenerationplatelet rich fibrin matrix.ridge preservationwound healing

Related Experiment Videos

Last Updated: Jun 22, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

  • Clinical and histological evaluations were conducted at multiple time points: 10 days, 2, 3, 6, and 12 weeks.
  • Healing progression and bone regeneration were assessed histologically.

    • Main Results:

    • PRFM and PRFM with membrane treatments demonstrated accelerated osseous fill by 3 weeks.
    • Sites treated with DFDBA showed minimal new bone formation at 6 weeks, with particles still present at 12 weeks.
    • PRFM-treated sites exhibited faster healing and complete osseous fill by 12 weeks.

    Conclusions:

    • Platelet-rich fibrin matrix (PRFM) alone may be the optimal graft material for ridge preservation.
    • PRFM facilitates faster healing compared to DFDBA.
    • Utilizing PRFM may eliminate the need for barrier membranes, simplifying procedures.