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Updated: Jun 22, 2026

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
Published on: July 11, 2025
A new approach for adipose tissue treatment and body contouring using radiofrequency-assisted liposuction
Malcolm Paul1, Robert Stephen Mulholland
1Aesthetic Plastic Surgery Institute, University of California, Irvine, CA 92660, USA. mpaulmd@hotmail.com
Abstract:
A new liposuction technology for adipocyte lipolysis and uniform three-dimensional tissue heating and contraction is presented. The technology is based on bipolar radiofrequency energy applied to the subcutaneous adipose tissue and subdermal skin surface. Preliminary clinical results, thermal monitoring, and histologic biopsies of the treated tissue demonstrate rapid preaspiration liquefaction of adipose tissue, coagulation of subcutaneous blood vessels, and uniform sustained heating of tissue.

