Expression and purification of APRIL by auto-induction

Sanjian Yu1, Yuxiong Wang, Yushan Liu

  • 1The key Laboratory of Molecular Medicine, the Ministry of Education, Shanghai Medical School, Fudan University, China.

Summary

A proliferation-inducing ligand (APRIL) is crucial for cell growth and immune responses, and is linked to cancer and autoimmune diseases. Researchers successfully produced biologically active APRIL, confirming its role in proliferation and receptor binding.

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