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[American ginseng compound liquor on retarding-aging process]
Zhong Xi Yi Jie He Za Zhi = Chinese Journal of Modern Developments in Traditional Medicine
|August 1, 1991
Summary
American ginseng compound liquor significantly improved aging symptoms, particularly Kidney-Yang deficiency, compared to American ginseng liquor alone. Both formulations enhanced antioxidant markers and prolonged functional age in individuals over sixty.
Area of Science:
- Gerontology
- Traditional Chinese Medicine
- Pharmacology
Background:
- Aging is associated with various physiological deficiencies, including Kidney-Yang, Kidney-Qi, and Kidney-Yin.
- American ginseng is recognized for its potential health benefits, but its efficacy in compound formulations for aging symptoms requires further investigation.
Purpose of the Study:
- To evaluate the efficacy of American ginseng compound liquor in managing age-related symptoms in individuals over sixty.
- To compare the effects of American ginseng compound liquor versus American ginseng liquor alone on specific aging-related deficiencies and physiological markers.
Main Methods:
- A single-blind, randomized controlled trial involving 71 participants aged over sixty.
- Participants were divided into a treated group (American ginseng compound liquor) and a control group (American ginseng liquor only).
- Evaluated total effective rates, specific deficiency improvement rates (Kidney-Yang, Kidney-Qi, Kidney-Yin), erythrocyte superoxide dismutase (SOD) activity, SOD/lipid peroxidation (LPO) ratio, and serum LPO content.
Main Results:
- The treated group showed a significantly higher total effective rate (88.89%) compared to the control group (68.57%) for aging symptoms (P < 0.05).
- American ginseng compound liquor demonstrated superior improvement in Kidney-Yang deficiency symptoms compared to the control group (P < 0.05).
- Both groups exhibited significant increases in SOD activity and SOD/LPO ratio, with a significant decrease in serum LPO (P < 0.001), indicating improved antioxidant status. The treated group also showed a reduction in functional age.
Conclusions:
- American ginseng compound liquor is more effective than American ginseng liquor alone in alleviating aging symptoms, especially Kidney-Yang deficiency.
- Both formulations contribute to improved antioxidant status and show potential in prolonging functional age.
- The findings support the use of American ginseng compound liquor as a therapeutic option for managing age-related decline.