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Updated: Jun 22, 2026

Chromosomics: Detection of Numerical and Structural Alterations in All 24 Human Chromosomes Simultaneously Using a Novel OctoChrome FISH Assay
Published on: February 6, 2012
Chromosomal analysis and identification based on optical tweezers and Raman spectroscopy: comment
Jimmy Bak1, Thomas M Jørgensen
1Optics and Plasma Research Department, Risø National Laboratory, Frederiksborgvej 399, 4000-Roskilde, Denmark. Jimmy.bak@risoe.dk
Abstract:
The authors of the work: 'Chromosomal analysis and identification based on optical tweezers and raman spectroscopy' [Opt. Express 14, 5385 (2006], claim that they have been able to identify and differentiate between three human chromosomes with an optical-tweezer - Raman Spectroscopic experimental (LTRS) set-up. The results and conclusions as they are presented in the paper are questionable, however, when the spectral data and data analysis are studied in greater detail.
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