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Updated: Jun 22, 2026

Chromosomics: Detection of Numerical and Structural Alterations in All 24 Human Chromosomes Simultaneously Using a Novel OctoChrome FISH Assay
Published on: February 6, 2012
Chromosomal analysis and identification based on optical tweezers and Raman spectroscopy: reply
Jenifer F Ojeda1, Changan Xie, Yong-Qing Li
1Department of Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27858-4353, USA. Jfo0628@ecu.edu
Abstract:
We appreciate the authors' comments in their reply: "On the identification of chromosomes with Raman spectroscopy: a critical comment" [Opt. Express 15, 5997 (2007)]. Their main concern with our paper is asking if the collected spectra have shown the identification or differentiation between three human chromosomes. We think this comment is flawed because the authors misunderstood the main points of the original paper and interpreted the presented spectra data (Fig. 3 and Table 1) incorrectly.
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