Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Operations for atrial fibrillation.

J L Cox1, J P Boineau, R B Schuessler

  • 1Department of Surgery, Washington University School of Medicine, Barnes Hospital, St. Louis, MO 63110.

Clinical Cardiology
|October 11, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Large diaphyseal-incorporating allograft prosthetic composites: when, how, and why : Treatment of advanced proximal humeral bone loss.

Der Orthopade·2017
Same author

The long-term follow-up of women treated for postnatal depression at a specialist day hospital compared to routine primary care.

International journal of psychiatry in clinical practice·2014
Same author

Health and salvation as the ethical ideal.

Journal of religion and health·2013
Same author

Karma and redemption: A religious approach to family violence.

Journal of religion and health·2013
Same author

Low ambient level uptake of(14)C-DDT by three species of marine phytoplankton.

Bulletin of environmental contamination and toxicology·2013
Same author

Multimodal imaging in systemic lupus erythematosus patients with diffuse neuropsychiatric involvement.

Lupus·2013

A novel surgical procedure effectively cures atrial fibrillation (AF), the most common heart arrhythmia, in all treated patients. This groundbreaking surgery offers a lasting solution for individuals unresponsive to conventional medical therapies.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Electrophysiology

Background:

  • Atrial fibrillation (AF) is a prevalent cardiac arrhythmia lacking effective treatments.
  • Existing medical and surgical therapies for AF have historically been limited.
  • Advancements in electrophysiological mapping have provided new insights into AF mechanisms.

Purpose of the Study:

  • To introduce and evaluate a novel surgical procedure for treating atrial fibrillation.
  • To assess the efficacy and safety of this new surgical approach.
  • To determine the long-term outcomes of patients undergoing the procedure.

Main Methods:

  • A multipoint computerized electrophysiological mapping system was utilized to study AF.
  • A new surgical procedure was developed based on mapping studies.

Related Experiment Videos

  • The procedure was performed on 22 patients with refractory paroxysmal or chronic atrial fibrillation/flutter between 1987 and 1991.

    • Main Results:

    • No operative deaths occurred; all perioperative morbidity resolved.
    • All 22 patients achieved a cure of atrial fibrillation solely through surgery.
    • One patient experienced a late, isolated episode of atrial flutter, managed with medication.
    • Postoperative atrial transport function was preserved, and patients showed significant clinical improvement.

    Conclusions:

    • The developed surgical procedure offers a definitive cure for atrial fibrillation.
    • This surgical intervention is safe and effective for patients refractory to antiarrhythmic drugs.
    • Preservation of atrial function and clinical improvement are key benefits of the procedure.