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Related Experiment Video

Updated: Jun 22, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

K P Balsara1, C R Shah, M Hussain

  • 1Department of GI and Minimal Access Surgery, Bhatia, Breach Candy and Jaslok Hospitals, Mumbai, India.

Journal of Minimal Access Surgery
|June 24, 2009
PubMed
Summary
This summary is machine-generated.

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Laparoscopic fundoplication (LF) offers good long-term relief for gastroesophageal reflux disease (GERD) symptoms. Careful patient selection is crucial for optimizing surgical outcomes and avoiding poor results.

Area of Science:

  • Minimally Invasive Surgery
  • Gastroenterology
  • Surgical Outcomes Research

Background:

  • Laparoscopic fundoplication (LF) is the preferred surgical treatment for gastroesophageal reflux disease (GERD).
  • Evidence suggests surgical intervention yields superior long-term outcomes compared to medical management for GERD.
  • This study retrospectively analyzes 8-year experience with LF to identify factors influencing surgical success.

Purpose of the Study:

  • To evaluate the long-term efficacy of laparoscopic fundoplication (LF) for gastroesophageal reflux disease (GERD).
  • To identify patient-specific variables that predict successful surgical outcomes.
  • To establish criteria for optimal patient selection for LF.

Main Methods:

  • Retrospective analysis of 85 patients who underwent LF for GERD between 1999 and 2007.
Keywords:
Gastro esophageal reflux disease (GERD)laparoscopic fundoplication

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Last Updated: Jun 22, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

  • Pre-operative assessments included endoscopy, barium study, esophageal manometry, and 24-hour pH monitoring.
  • Patient follow-up involved interviews and/or phone calls, with outcomes graded using a scoring system.

    • Main Results:

    • Laparoscopic fundoplication was successfully completed in 84% of patients; one conversion to open surgery due to bleeding.
    • Overall, 77% of patients reported a good outcome, while 23% experienced poor results.
    • Predictors of a good surgical response included positive response to proton pump inhibitors (PPIs), volume reflux, and a pH score >14.

    Conclusions:

    • Laparoscopic fundoplication provides significant long-term symptom relief for patients with GERD.
    • Strict patient selection criteria are essential for maximizing the success of LF.
    • Inadequate patient selection can lead to suboptimal or adverse surgical outcomes.