Related Experiment Video
Updated: Jun 22, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
Depressive symptoms and perception of quality of life in Parkinson's disease
Paula Scalzo1, Arthur Kummer, Francisco Cardoso
1Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte MG, Brazil.
Background:
Depression has been proposed as a major contributor to poor quality of life (QoL) in Parkinson's disease (PD).
Objective:
To evaluate the relationship between depressive symptoms and QoL in subjects with PD.
Method:
Beck Depression Inventary (BDI) was used to evaluate depressive symptoms and Parkinson's Disease Quality of Life Questionnaire (PDQ-39) to assess the perception of the QoL.
Results:
Thirty seven patients (19 male/ 18 female) with a typical onset PD and mean disease duration of 7.7 years were studied. Higher scores on BDI correlated with poorer perception of the QoL. This association occurred at the expense of the following PDQ39 domains: mobility, activities of daily living, social support, cognition and emotional well-being dimensions. PD severity also correlated with QoL.
Conclusion:
Our study corroborates the assumption that depressive symptoms contributed significantly to QoL in PD.
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Parkinson's Disease: Overview
Parkinson Disease ll: Pathophysiology
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Depressive Disorders: MDD and Dysthymia
Parkinson Disease l: Introduction