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Updated: Jun 22, 2026

Collection of Human Follicular Fluid, Follicle Somatic Cells, and Immature Oocytes from Individuals Undergoing In Vitro Fertilization
Published on: October 24, 2025
Follicular and luteal phase endometrial thickness and echogenic pattern and pregnancy outcome in oocyte donation
Matthew A Barker1, Lynn M Boehnlein, Peter Kovacs
1Department of Obstetrics and Gynecology, Good Samaritan Hospital, 3219 Clifton Ave. Suite #100, Cincinnati, OH 45220, USA. Matthew_Barker@trihealth.com
Purpose:
To study the effect of endometrial thickness (ET) and echogenic pattern (EP) in oocyte donation cycles upon pregnancy outcomes.
Methods:
Seventy-nine cycles resulting in blastocyst embryo transfer were evaluated. Donors underwent ovarian hyperstimulation using rFSH and GnRH-antagonist. Recipients were synchronized to donors using GnRH-agonist down-regulation followed by fixed dose of estrogen (E2) and progesterone (P4) following hCG. Transvaginal ultrasound (US) obtained ET and EP 10-11 days after initiation of E2 and on day of embryo transfer. Primary outcome was ET and EP in pregnant and non-pregnant cycles. Stimulation and embryology data was analyzed in donors to assess differences prior to transfer.
Results:
Fifty-nine cycles resulted in clinical pregnancy. No differences were observed in pregnant vs. non-pregnant cycles in proliferative or secretory ET and EP. Similar baseline and stimulation characteristics were found in pregnant and non-pregnant cycles. Regression analysis showed end thickness were not predictive of pregnancy outcomes.
Conclusions:
Endometrial characteristics in recipients prior to and following progesterone were not predictive of pregnancy outcomes.
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