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Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Inflammatory bowel diseases in pregnancy]
Krzysztof Gutkowski1, Marek Hartleb
1Katedra i Klinika Gastroenterologii i Hepatologii Slaskiego Uniwersytetu Medycznego. kgutski@intertele.pl
Inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease, affect many women of reproductive age. This review covers IBD in pregnancy, its effects, and safe medication options.
Area of Science:
- Gastroenterology
- Immunology
- Obstetrics
Context:
- Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases (IBD).
- IBD affects women of reproductive age, peaking between 20-40 years.
- Etiology involves genetic, immunologic, and environmental factors leading to chronic gut inflammation.
Purpose:
- To review the impact of IBD on pregnancy.
- To discuss risks of obstetric complications in pregnant IBD patients.
- To evaluate the safety of pharmacotherapy during pregnancy for IBD.
Summary:
- Diagnosis of IBD involves biochemical, endoscopic, and histologic assessments.
- Treatment relies on long-term anti-inflammatory and immunosuppressive therapies.
- Understanding IBD's influence on pregnancy is crucial for managing risks.
Impact:
- Optimizing IBD management in pregnant women reduces obstetric complications.
- Ensures safer medication choices for both mother and fetus.
- Improves outcomes for women with IBD during their reproductive years.
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