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Related Experiment Video

Updated: Jun 22, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Automatic retinal blood flow calculation using spectral domain optical coherence tomography.

Hassan Wehbe, Marco Ruggeri, Shuliang Jiao

    Optics Express
    |June 25, 2009
    PubMed
    Summary

    Researchers developed a new method to determine the Doppler angle for accurate blood flow speed measurement using Optical Doppler Tomography (ODT) and spectral-domain Optical Coherence Tomography (OCT). This technique enhances diagnosis of blinding diseases like glaucoma.

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    Area of Science:

    • Ophthalmology
    • Biomedical Engineering
    • Medical Imaging

    Background:

    • Optical Doppler Tomography (ODT) measures blood flow speed via Doppler shift from moving blood cells.
    • Accurate blood flow velocity calculation requires determining the Doppler angle.
    • Existing methods lack efficient Doppler angle extraction for retinal vasculature.

    Purpose of the Study:

    • To develop and validate a novel technique for extracting the Doppler angle from 3D spectral-domain OCT data.
    • To enable precise absolute blood flow velocity measurements in retinal vessels.
    • To improve the diagnosis and study of blinding diseases such as glaucoma.

    Main Methods:

    • A blood vessel shadowgram technique was used to extract lateral coordinates and vessel diameter from OCT images.

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    Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
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    Published on: March 26, 2020

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    Last Updated: Jun 22, 2026

    Doppler Optical Coherence Tomography of Retinal Circulation
    10:46

    Doppler Optical Coherence Tomography of Retinal Circulation

    Published on: September 18, 2012

    Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
    07:23

    Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

    Published on: March 26, 2020

  • A circular averaging filter was applied to ODT images to determine the vessel's depth coordinate.
  • The Doppler angle was calculated using the extracted 3D vessel coordinates.

    • Main Results:

    • The developed technique successfully extracted the Doppler angle from 3D OCT/ODT data.
    • Demonstrated application in retinal blood flow measurements.
    • Validated the capability to determine absolute blood flow velocity.

    Conclusions:

    • The novel Doppler angle extraction method provides accurate blood flow velocity measurements.
    • This technique has significant potential for the study and diagnosis of retinal vascular diseases.
    • Improved ODT/OCT analysis can aid in early detection and management of conditions like glaucoma.